EFFECTS OF ACUTE PORTAL-HYPERTENSION BY PORTAL VENOUS STENOSIS ON SYSTEMIC HEMODYNAMICS IN DOGS

被引：12
|
作者：
MORIURA, S [1 ]
NIMURA, Y [1 ]
KATO, M [1 ]
SATO, T [1 ]
SHIONOYA, S [1 ]
机构：
[1] NAGOYA UNIV,SCH MED,DEPT SURG 1,SHOWA KU,NAGOYA,AICHI 466,JAPAN
来源：
EUROPEAN SURGICAL RESEARCH | 1990年 / 22卷 / 02期
关键词：
Acute portal hypertension; Cardiac output; Dog; Hepatectomy; Liver circulation;
D O I：
10.1159/000129090
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Effects of acute portal hypertension on systemic hemodynamics after hepatectomy were evaluated by portal venous stenosis (PVS) model in dogs. In protocol 1, portal hypertension of about twice portal venous pressure (PVP) decreased cardiac output (CO) and left atrial pressure (LAP) by 24.5% (p < 0.01) and 1.0 mm Hg (p < 0.01), respectively. In protocol 2, stepwise PVS demonstrated that CO change (%) and LAP change (mm Hg) were inversely proportional to PVP change (r = -0.937 and -0.883, respectively). The ratio of CO change to LAP change with stepwise PVS was comparable to that obtained by repeated hemorrhage in protocol 3. The present study shows that low CO with portal hypertension is caused by a reduction of venous return to the heart. © 1990 S. Karger AG, Basel.
引用
收藏
页码：113 / 119
页数：7
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