MARKED REDUCTION OF FREE-RADICAL GENERATION AND CONTRACTILE DYSFUNCTION BY ANTIOXIDANT THERAPY BEGUN AT THE TIME OF REPERFUSION - EVIDENCE THAT MYOCARDIAL STUNNING IS A MANIFESTATION OF REPERFUSION INJURY

被引：569
作者：
BOLLI, R
JEROUDI, MO
PATEL, BS
ARUOMA, OI
HALLIWELL, B
LAI, EK
MCCAY, PB
机构：
[1] UNIV LONDON KINGS COLL,DEPT BIOCHEM,LONDON WC2R 2LS,ENGLAND
[2] OKLAHOMA MED RES FDN,DIV MOLEC TOXICOL,OKLAHOMA CITY,OK 73104
来源：
CIRCULATION RESEARCH | 1989年 / 65卷 / 03期
关键词：
D O I：
10.1161/01.RES.65.3.607
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：607 / 622
页数：16
相关论文
共 56 条
[11]   THE STUNNED MYOCARDIUM - PROLONGED, POST-ISCHEMIC VENTRICULAR DYSFUNCTION [J].
BRAUNWALD, E ;
KLONER, RA .
CIRCULATION, 1982, 66 (06) :1146-1149
[12]  
BUTLER J, 1982, J BIOL CHEM, V257, P10749
[13]   PROLONGED ABNORMALITIES OF LEFT-VENTRICULAR DIASTOLIC WALL THINNING IN THE STUNNED MYOCARDIUM IN CONSCIOUS DOGS - TIME COURSE AND RELATION TO SYSTOLIC FUNCTION [J].
CHARLAT, ML ;
ONEILL, PG ;
HARTLEY, CJ ;
ROBERTS, R ;
BOLLI, R .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1989, 13 (01) :185-194
[14]   EVIDENCE FOR A PATHOGENETIC ROLE OF XANTHINE-OXIDASE IN THE STUNNED MYOCARDIUM [J].
CHARLAT, ML ;
ONEILL, PG ;
EGAN, JM ;
ABERNETHY, DR ;
MICHAEL, LH ;
MYERS, ML ;
ROBERTS, R ;
BOLLI, R .
AMERICAN JOURNAL OF PHYSIOLOGY, 1987, 252 (03) :H566-H577
[15]   ANTIARTHRITIC DRUGS CONTAINING THIOL-GROUPS SCAVENGE HYPOCHLORITE AND INHIBIT ITS FORMATION BY MYELOPEROXIDASE FROM HUMAN-LEUKOCYTES - A THERAPEUTIC MECHANISM OF THESE DRUGS IN RHEUMATOID-ARTHRITIS [J].
CUPERUS, RA ;
MUIJSERS, AO ;
WEVER, R .
ARTHRITIS AND RHEUMATISM, 1985, 28 (11) :1228-1233
[16]  
DEVI PU, 1983, J NUCL MED ALLIED S, V27, P327
[17]  
DORFMAN LM, 1973, NBS REFERENCE DATA S, V46, P1
[18]   TISSUE SULFHYDRYL GROUPS [J].
ELLMAN, GL .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1959, 82 (01) :70-77
[19]  
FARHATAZIZ RAB, 1977, NBS DATA REFERENCE S, V59, P14
[20]   MYOCARDIAL NEUTROPHIL ACCUMULATION DURING REPERFUSION AFTER REVERSIBLE OR IRREVERSIBLE ISCHEMIC-INJURY [J].
GO, LO ;
MURRY, CE ;
RICHARD, VJ ;
WEISCHEDEL, GR ;
JENNINGS, RB ;
REIMER, KA .
AMERICAN JOURNAL OF PHYSIOLOGY, 1988, 255 (05) :H1188-H1197
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