EFFECT OF ALKYL CHAIN-LENGTH ON ACID - AMIDE HYDROGEN-BONDING

The hydrogen bonding motifs in four families of carboxyl acid amides - p-amido benzoic, phenylamido carboxylic, benzoylamino carboxylic, and phthalimido carboxylic acids - are examined. Available structural data suggested that the dominant factor in motif determination might be alkyl chain length. Additional representative structures were determined to investigate this hypothesis, revealing that, although important, chain length alone is not responsible for the observed hydrogen bond motif.