In this paper, we investigate the geochemical and isotope properties of the Jeongeup foliated granite (hereafter, the JFG) in the Jeongeup area, aiming at establishing the movement age of the Honam shear zone by U-Pb sphene geochronology. hi the AMF diagram, the JFG corresponds to the calc alkalic rock series, and belongs to the magnesia region in the diagram of silica versus FeOtotal/(FeOtotal+MgO). Additionally, in the Rb-Ba-Sr diagram, it is classified as granodiorite and anomalous granite with distinctive negative Eu-anomaly in the REE patterns. According to the silica and trace element contents, the JFG falls on the type VAG+syn-COLCS which implies that this was formed under the circumstance of compressional continental margin or volcanic arc. Nd-143/Nd-144 isotope ratios range from 0.511495 to 0.511783 and T-DM are calculated to be about 1.68 similar to 2.36 Ga. U-Pb sphene ages of the JFG are 172.9 +/- 1.7 Ma and 170.7 +/- 2.8 Ma, based on U-238-Pb-206 and U-235-Pb-207 ages, respectively. Presumably, the dextral ductile shearing in the Jeongeup area has occurred after 173 Ma.