DERACEMIZATION OF A PHOSPHINE OXIDE VIA ENANTIOSELECTIVE PROTONATION

被引：26
|
作者：
VEDEJS, E
GARCIARIVAS, JA
机构：
[1] Chemistry Department, University of Wisconsin, Madison
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 22期
关键词：
D O I：
10.1021/jo00101a008
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Treatment of the phosphine oxide anion 2 with the keto aniline 3c affords (S)-1 with 81-83% ee, and one crystallization upgrades the material to (S)-1 with > 99% ee (78% overall yield).
引用
收藏
页码：6517 / 6518
页数：2
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