Compared 22 siblings of autistic boys and 34 other siblings on measures of depression, social adjustment, and the amount of child care and domestic responsibility the siblings carry within the family. The relationship between sibling gender, age, birth order, qualities of the boy with autism, and family characteristics, and siblings' scores on the above measures were examined. Results of this research showed that siblings of autistic boys scored significantly higher on depression than the comparison group, but not on problems of social adjustment. There were no statistically significant gender differences; however, different gender-related patterns emerged on the correlates which may be of theoretical significance for future studies.