A NEW GENE NESTED WITHIN THE DUNCE GENETIC UNIT OF DROSOPHILA-MELANOGASTER

被引：21
|
作者：
FURIA, M [1 ]
DIGILIO, FA [1 ]
ARTIACO, D [1 ]
GIORDANO, E [1 ]
POLITO, LC [1 ]
机构：
[1] CNR,IST BIOCHIM PROT ENZIMOL,NAPLES,ITALY
来源：
NUCLEIC ACIDS RESEARCH | 1990年 / 18卷 / 19期
关键词：
D O I：
10.1093/nar/18.19.5837
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The molecular organization of the dunce gene of Drosophila melanogaster has proved to be particularly complex, with two divergently transcribed genes, Sgs-4 and Pig-1, nested within its 79 kb Intron (1). Here we report the identification and the molecular characterization of a third gene nested within the transcription unit of dunce. This newly identified gene is located nearly 6 kb downstream Pig-1, within a more upstream dunce intron. The gene is developmentally regulated and transcribed with the same polarity of dunce; several lines of evidence indicate that it might encode for a salivary gland secreted (Sgs) protein. © 1990 Oxford University Press.
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页码：5837 / 5841
页数：5
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