CARBOPLATIN IN PREVIOUSLY TREATED MULTIPLE-MYELOMA - A CANCER AND LEUKEMIA GROUP-B PHASE-II TRIAL

被引：2

作者：

OMURA, GA

PERRI, RT

PETERSON, B

SCHIFFER, CA

机构：

[1] UNIV ALABAMA,BIRMINGHAM,AL 35294

[2] UNIV MINNESOTA,MINNEAPOLIS,MN 55455

[3] DUKE UNIV,DURHAM,NC 27706

[4] UNIV MARYLAND,BALTIMORE,MD 21201

来源：

AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS | 1994年 / 17卷 / 03期

关键词：

CARBOPLATIN; CHEMOTHERAPY; TOXICITY;

D O I：

10.1097/00000421-199406000-00003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Carboplatin 400 Mg/M2 per month was evaluated as a single agent in 15 patients with multiple myeloma who had had one prior chemotherapy regimen. All but three were judged to have had some degree of refractoriness to prior therapy. Hematologic toxicity was frequent and sometimes severe. There were no responses. Further evaluation of standard-dose single-agent carboplatin in refractory myeloma does not appear warranted.

引用

页码：196 / 198

页数：3

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