ANTITUMOR-ACTIVITY OF HOMO-AZA-STEROIDAL ESTERS OF P-N,N-BIS(2-CHLOROETHYL)AMINOPHENOXYACETIC ACID

被引：0
|
作者：
CATSOULACOS, P
CATSOULACOS, D
机构：
来源：
ANTICANCER RESEARCH | 1993年 / 13卷 / 04期
关键词：
HOMO-AZA-STEROIDAL ESTERS OF PHENOXYACETIC ACID MUSTARD; ANTITUMOR ACTIVITY;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The homo - aza - steroidal esters of carboxylic derivatives of N, N - bis (2 - chloroethyl) aniline are reviewed. In particular, we discuss the antitumor activity of the esters of homo - aza steroids in which the p - N, N - bis (2 - chloroethyl) aminophenoxyacetic acid is linded to the C - 3 or C - 17 position, while the lactam nucleus is linked to the D or A ring of the modified steroid respectively. The current literature indicates clearly that the potential of these esters is due to the synergistic activity of both the lactam and the p - N, N - bis (2 - chloroethyl) aminophenoxyacetic acid.
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页码：1203 / 1208
页数：6
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