Blood and marrow stem cells transplantation in multiple sclerosis. Present and future in its use and selection of patients

被引：0

作者：

Skromne Eisenberg, E. ^{[1
]}

Rivera Olmos, V. M. ^{[2
]}

Ordonez Boschetti, L. ^{[1
]}

Ontaneda Johnson, D. ^{[1
]}

机构：

[1] Baylor Coll Med, Invest Esclerosis Multiple, Houston, TX 77030 USA

[2] Methodist Hosp, Baylor Coll Med, Maxine Mesinger Multiple Sclerosis Clin, Neurol, Houston, TX USA

来源：

REVISTA MEXICANA DE NEUROCIENCIA | 2006年 / 7卷 / 02期

关键词：

Blood and marrow stem cells transplantation; multiple sclerosis;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Multiple sclerosis (MS) is a disease with an autoinmune pathophysiology. A new and promising treatment in this group of patients is the blood and marrow stem cells transplant at ion which is currently an experimental treatment with evident immuno-suppressant effects. It has not been demonstrated any effect on neurodegeneration and it is preferred to use this procedure as a non-conventional treatment of multiple sclerosis. Select ion of patients should be strict, mainly in patients with moderate severity and an important inflammatory component. It is not a rescue treatment because its utility in progressive forms or advanced MS has not been demonstrated and the risk is high. This review includes an analysis of the current protocols and their results.

引用

页码：164 / 169

页数：6

共 50 条

[31] Stem cell transplantation in multiple sclerosis: current status and future prospects
Martino, Gianvito
Franklin, Robin J. M.
Baron-Van Evercooren, Anne
Kerr, Douglas A.
NATURE REVIEWS NEUROLOGY, 2010, 6 (05) : 247 - 255
[32] Reserves and functional characteristics of bone marrow stem cells and hematopoiesis supporting capacity of marrow stromal cells in patients with multiple sclerosis
Papadaki, HA
Tzagournissakis, M
Mastorodemos, V
Pontikoglou, C
Plaitakis, A
NEUROLOGY, 2005, 64 (06) : A195 - A196
[33] Allogeneic transplantation of unmanipulated peripheral blood stem cells in patients with multiple myeloma
I Majolino
P Corradini
R Scimè
A Santoro
C Tarella
AM Cavallaro
A Palumbo
A Indovina
D Caracciolo
M Boccadoro
R Marcenò
A Pileri
Bone Marrow Transplantation, 1998, 22 : 449 - 455
[34] Allogeneic transplantation of unmanipulated peripheral blood stem cells in patients with multiple myeloma
Majolino, I
Corradini, P
Scimè, R
Santoro, A
Tarella, C
Cavallaro, AM
Palumbo, A
Indovina, A
Caracciolo, D
Boccadoro, M
Marcenò, R
Pileri, A
BONE MARROW TRANSPLANTATION, 1998, 22 (05) : 449 - 455
[35] Bone marrow mesenchymal stem cells intrathecal transplantation in patients with progressive multiple sclerosis-1-year follow-up
Swiderek-Matysiak, M.
Wojtkiewicz, J.
Habich, A.
Selmaj, I.
Maksymowicz, W.
Selmaj, K.
EUROPEAN JOURNAL OF NEUROLOGY, 2016, 23 : 207 - 207
[36] Allogeneic mesenchymal stem cells transplantation in treatment of multiple sclerosis
Liang, J.
Zhang, H.
Hua, B.
Wang, H.
Wang, J.
Han, Z.
Sun, L.
MULTIPLE SCLEROSIS JOURNAL, 2009, 15 (05) : 644 - 646
[37] THE USE OF BONE MARROW DERIVED MESENCHYMAL STROMAL CELLS FOR TREATMENT OF PATIENTS WITH MULTIPLE SCLEROSIS AND NEURODEGENERATIVE DISORDERS - ACHIEVEMENTS AND FUTURE GOALS
Slavin, S.
Brodie, C.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2012, 18 (02) : S257 - S258
[38] Hematopoietic stem cell transplantation. Bone marrow and blood stem cells
von Bergwelt-Baildon, M.
Holtick, U.
Hallek, M. J.
Scheid, C.
INTERNIST, 2014, 55 (11): : 1306 - 1312
[39] Bone marrow and peripheral blood stem cell transplantation in multiple myeloma
Gahrton, G
ANNALS OF ONCOLOGY, 1997, 8 (03) : 219 - 221
[40] Normal bone marrow hematopoietic stem cell reserves and normal stromal cell function support the use of autologous stem cell transplantation in patients with multiple sclerosis
Papadaki, HA
Tsagournisakis, M
Mastorodemos, V
Pontikoglou, C
Damianaki, A
Pyrovolaki, K
Stamatopoulos, K
Fassas, A
Plaitakis, A
Eliopoulos, GD
BONE MARROW TRANSPLANTATION, 2005, 36 (12) : 1053 - 1063

← 1 2 3 4 5 →