ACCURACY OF AMNIOTIC-FLUID TESTING BEFORE 21 WEEKS GESTATION IN PRENATAL-DIAGNOSIS OF CONGENITAL CYTOMEGALOVIRUS-INFECTION

被引：79

作者：

DONNER, C ^{[1
]}

LIESNARD, C ^{[1
]}

BRANCART, F ^{[1
]}

RODESCH, F ^{[1
]}

机构：

[1] FREE UNIV BRUSSELS,ERASME UNIV HOSP,VIROL LAB,B-1070 BRUSSELS,BELGIUM

来源：

PRENATAL DIAGNOSIS | 1994年 / 14卷 / 11期

关键词：

CYTOMEGALOVIRUS; AMNIOCENTESIS; PRENATAL DIAGNOSIS; FETUS;

D O I：

10.1002/pd.1970141108

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Cytomegalovirus (CMV) is the most common cause of intrauterine infection. Recent publications show amniocentesis to have an 81-100 per cent sensitivity in antenatal diagnosis after 21 weeks' gestation. Testing before 21 weeks' gestation is less well documented. We performed 36 amniocenteses between 14 and 20 weeks' gestation. The sensitivity was 45 per cent and the specificity 100 per cent. Implications and possible causes of this low sensitivity are discussed.

引用

页码：1055 / 1059

页数：5

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