SELF-ASSOCIATION OF VIOLAMYCIN (VBI)

被引：7
|
作者：
ONCESCU, T [1 ]
ILIESCU, I [1 ]
DEMAYER, L [1 ]
机构：
[1] MAX PLANCK INST BIOPHYS CHEM,W-3400 GOTTINGEN,GERMANY
来源：
BIOPHYSICAL CHEMISTRY | 1993年 / 47卷 / 03期
关键词：
VIOLAMYCIN; SELF-ASSOCIATION; SPECTROPHOTOMETRY; TEMPERATURE JUMP; ANTHRACYCLINE; DIMERIZATION;
D O I：
10.1016/0301-4622(93)80053-L
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Violamycin (VBI) self-associate-s in aqueous solution at concentration greater than 7 X 10(-5) M. We report in this paper visible spectrophotometric and kinetic experiments that characterize this self-association. We started from a simple dimerization model supported by our experimental data, and we used different methods described in literature for the computation of the dimeric extinction coefficient epsilon(d) at various wavelengths and the dimerization constant K(d) = 9300 M-1.
引用
收藏
页码：277 / 283
页数：7
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