CHROMOSOMAL ANALYSIS OF COLONIC ADENOMATOUS POLYPS

被引：24
|
作者：
LONGY, M
SAURA, R
SCHOULER, L
MAUHIN, C
GOUSSOT, JF
GRISON, O
COUZIGOU, P
机构：
[1] USN HAUT LEVEQUE,SERV GASTROENTEROL,PESSAC,FRANCE
[2] HOP ST ANDRE,ANAT PATHOL LAB,F-33075 BORDEAUX,FRANCE
来源：
CANCER GENETICS AND CYTOGENETICS | 1990年 / 49卷 / 02期
关键词：
D O I：
10.1016/0165-4608(90)90149-5
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Chromosomal analysis of 25 colonic adenomatous polyps was performed by a direct method similar to that used in prenatal diagnosis of chromosomal aberration on chorionic villi. Fourteen lesions showed an abnormal karyotype. Two changes were recurrent: trisomy 7 (observed in eight cases) and trisomy 13 (observed in seven cases). No monosomy of the short arm of chromosome 17 was observed even at the level of two polyps with in situ carcinoma lesions. © 1990.
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页码：249 / 257
页数：9
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