PRENYLATED XANTHONES FROM GARCINIA-LIVINGSTONEI

被引：42

作者：

SORDATDISERENS, I

ROGERS, C

SORDAT, B

HOSTETTMANN, K

机构：

[1] SWISS INST EXPTL CANC RES, CH-1066 EPALINGES, SWITZERLAND

[2] UNIV DURBAN WESTVILLE, DEPT CHEM, DURBAN 4000, SOUTH AFRICA

来源：

PHYTOCHEMISTRY | 1992年 / 31卷 / 01期

关键词：

GARCINIA-LIVINGSTONEI; GUTTIFERAE; ROOT BARK; PRENYLATED XANTHONES; 2D NMR; ANTIFUNGAL; CYTOINHIBITION;

D O I：

10.1016/0031-9422(91)83061-O

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Five prenylated xanthones have been isolated from the root bark of Garcinia livingstonei of which four are novel natural products. The xanthone, 12b-hydroxy-des-D-garcigerrin A was previously isolated from G. gerrardii. Structure elucidation was achieved by a combination of one- and two-dimensional NMR spectroscopic techniques, mass spectroscopy and chemical methods. Two compounds are fungicidal against Cladosporium cucumerinum, a plant pathogenic fungus, whereas a third shows growth inhibitory activity against human colon carcinoma cell lines.

引用

页码：313 / 316

页数：4

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