Mitochondrial DNA control region in native population from the province of Jujuy (northwestern Argentina)

被引：1
|
作者：
Cardoso, Sergio [1 ]
Merino, Maite [1 ]
Gomez, Luis [2 ]
Alfonso-Sanchez, Miguel A. [1 ]
Dipierri, Jose E. [3 ]
Alfaro, Emma [3 ]
Valverde, Laura [1 ]
Odriozola, Adrian [1 ]
Bravi, Claudio M. [4 ]
Pena, Jose A. [2 ]
de Pancorbo, Marian M. [1 ]
机构：
[1] Univ Basque Country, Fac Farm, Dpto Z Biol Celular, BIOMICS Res Grp, Paseo Univ 7, Vitoria 01006, Spain
[2] Univ Basque Country, Fac Ciencia & Tecnol, Dpto Genet Antropol Fis & Fisiol Anim, Leioa, Spain
[3] Univ Nacl Jujuy, Inst Biol Altura, San Salvador De Jujuy, Argentina
[4] Inst Multidisciplinario Biol Celular, CONICET, Lab Genet Mol Poblac, La Plata, Buenos Aires, Argentina
来源：
FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES | 2009年 / 2卷 / 01期
关键词：
Mitochondrial DNA; Control region; Haplogroup; Native American; Argentina;
D O I：
10.1016/j.fsigss.2009.08.182
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The province of Jujuy is located in northwestern Argentina. We analyzed mitochondrial DNA (mtDNA) haplogroup composition in 100 autochthonous individuals living at altitudes between 1200 and 3500 m above sea level, in San Salvador de Jujuy, Quebrada de Humahuaca and Puna. The purpose was to explore the influence of non-Native American maternal lineages. Additionally, we evaluated the efficacy of analyzing the entire mtDNA control region to increase its power of discrimination with forensic purposes. Results showed that the population sample was entirely composed by Native American haplogroups, with haplotypes belonging to haplogroup B as the most common lineages. Analysis of the entire mtDNA D-loop region proved to be useful to increase the power of discrimination provided by the analysis of HVS-I and HVS-II segments and to refine haplogroup assignment. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：340 / 341
页数：2
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