POLYCYCLIC AROMATIC ALKALOIDS .6. A REGIOSELECTIVE SYNTHESIS OF AZAFLUORENONE ALKALOIDS

被引：0
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作者：
BRACHER, F
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来源：
SYNLETT | 1991年 / 02期
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
6-Methoxyonychine 2 (8-methoxy-4-methyl-5H-indeno[1,2-b]pyridin-5-one) is obtained regioselectively from the biaryl 9 [2-(2-bromo-5-methoxyphenyl)-4-methyl-3-pyridinecarboxylic acid] via a Parham-type cyclisation. Alternatively, 9 can be converted to the unnatural isomer 8-methoxyonychine 11 by a simple two-step procedure (cyclisation and debromination).
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页码：95 / 96
页数：2
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