FORMULATION AND EVALUATION OF HERBAL ANTISEPTIC - HEMOSTATIC SOLUTION

Traditionally Used solutions for the treatment of Cuts, Open wounds,Abrasions of skin, Incisions are only having the antiseptic (antimicrobial ) activity but they do not stop the bleeding; hence to overcome this problem we are developed a formulation by formulating the number of batches by designing the23 factorial design of herbals Azadirachta indica (Neem), Curcuma longa (Turmeric) and Acacia catechu (Kattha) to act as a antiseptic and hemostatic by applying solution on the cuts and wounds . The plants have been reported in the literature as having good antimicrobial, anti-inflammatory and Hemostatics (Astringent) Activity. The prepared formulation was evaluated for various parameters like appearance, colour, pH, Consistency, Viscosity and antimicrobial activity. The formulation of Batch# F4 was compared with the marketed preparation Betadine (5 % Povidone Iodine). It is a very good attempt to establish the herbal antiseptic-Hemostatic Solution containing Extracts of Azadirachta indica (Neem) ,Curcuma longa (Turmeric) and Acacia catechu (Kattha) . Antiseptic-Hemostatic Solution was successfully designed and developed after extensive manufacturing and evaluation process by specialized techniques for evaluation of antiseptic -hemostatic activity in vitro