ASPIRIN-INDUCED NEUTROPHIL CHEMOTACTIC ACTIVITY (NCA) IN PATIENTS WITH ASPIRIN-SENSITIVE URTICARIA AFTER DESENSITIZATION TO THE DRUG

被引：0
|
作者：
GRZELEWSKARZYMOWSKA, I
SZMIDT, M
ROZNIECKI, J
GRZEGORCZYK, J
机构：
来源：
JOURNAL OF INVESTIGATIONAL ALLERGOLOGY & CLINICAL IMMUNOLOGY | 1994年 / 4卷 / 01期
关键词：
ASPIRIN-SENSITIVE URTICARIA; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; NEUTROPHIL CHEMOTACTIC ACTIVITY; ASPIRIN DESENSITIZATION;
D O I：
暂无
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
The increase in neutrophil chemotactic activity (NCA) is related to mast cell degranulation. This study was performed in 10 patients in whom aspirin-induced urticaria was connected with increased NCA. A state of tolerance to aspirin (ASA) was achieved by administering incremental doses of acetylsalicylic acid. In none of the examined Patients was an increase in NCA observed after 600 mg of ASA given after desensitization. The authors conclude that in patients with ASA-induCed urticaria, mast cell degranulation does not occur after ASA desensitization.
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页码：28 / 31
页数：4
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