Treatment of Oral Crohn's Disease with Infliximab

被引：0
|
作者：
Conteas, Chris N. [1 ]
Romberg, Christopher [2 ]
机构：
[1] Los Angeles Med Ctr, Dept Gastroenterol, Los Angeles, CA 90057 USA
[2] Los Angeles Med Ctr, Dept Internal Med, Los Angeles, CA 90057 USA
来源：
PRACTICAL GASTROENTEROLOGY | 2005年 / 29卷 / 10期
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D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Crohn's disease (CD) is a chronic inflammatory condition that is able to affect any portion of the digestive tract from the mouth to the anus. Oral Crohn's disease (OCD) is a well-documented extra-intestinal manifestation of CD, first described in 1969 by Dudney and Todd (1). Numerous published case reports and series have documented this condition's inconsistent and often disappointing response to traditional CD treatment modalities. More recently, several case reports have documented success in the treatment of OCD with infliximab, a chimeric monoclonal antibody against tumor necrosis factor alpha (2-8) (TNF-alpha). Here we report a case of severe OCD successfully treated with infliximab.
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页码：90 / 96
页数：5
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