Crystal structure of 2-cyclohexyl-1,3-thiazolo[4,5-b]pyridine

被引:1
|
作者
El-Hiti, Gamal A. [1 ]
Smith, Keith [2 ]
Hegazy, Amany S. [2 ]
Ajarim, Mansour D. [3 ]
Kariuki, Benson M. [2 ]
机构
[1] King Saud Univ, Dept Optometry, Coll Appl Med Sci, Cornea Res Chair, POB 10219, Riyadh 11433, Saudi Arabia
[2] Cardiff Univ, Sch Chem, Cardiff CF10 3AT, S Glam, Wales
[3] Minist Interior, Criminal Evidence, Riyadh 11632, Saudi Arabia
关键词
crystal structure; cyclohexane; thiazolopyridine derivatives; thiazolo[4,5-b]pyridine;
D O I
10.1107/S2056989015019106
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
In the title compound, C12H14N2S, the cyclohexane ring adopts a chair conformation with the exocyclic C-C bond in an equatorial orientation. The mean plane through the cyclohexane ring (all atoms) is twisted from the thiazolopyridine ring system (r.m.s. deviation = 0.013 angstrom) by 39.57 (6)degrees. In the crystal, molecules form (100) sheets, although there are no specific directional interactions between them. The crystal stucture was refined as a two-component perfect twin.
引用
收藏
页码:O866 / +
页数:6
相关论文
共 50 条
  • [1] Crystal structure of 2-tert-butyl-1,3-thiazolo[4,5-b]pyridine
    El-Hiti, Gamal A.
    Smith, Keith
    Hegazy, Amany S.
    Masmali, Ali M.
    Kariuki, Benson M.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2014, 70 : O932 - +
  • [2] Crystal structure of 2-(2-methylphenyl)-1,3-thiazolo[4,5-b]pyridine
    El-Hiti, Gamal A.
    Smith, Keith
    Hegazy, Amany S.
    Alanazi, Saud A.
    Kariuki, Benson M.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2015, 71 : O562 - +
  • [3] Crystal structure of 2-(1-methylethyl)-1,3-thiazolo[4,5-b]pyridine
    El-Hiti, Gamal A.
    Smith, Keith
    Hegazy, Amany S.
    Alanazi, Saud A.
    Kariuki, Benson M.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2015, 71 : O272 - U222
  • [4] Crystal structure of 2-(3-nitrophenyl)-1,3-thiazolo[4,5-b]pyridine
    El-Hiti, Gamal A.
    Smith, Keith
    Hegazy, Amany S.
    Ajarim, Mansour D.
    Kariuki, Benson M.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2015, 71 : O877 - +
  • [5] Crystal structure of 2-(4-methoxyphenyl)-1,3-thiazolo[4,5-b]pyridine, C13H10N2OS
    El-Hiti, Gamal A.
    Smith, Keith
    Hegazy, Amany S.
    Alanazi, Saud A.
    Kariuki, Benson M.
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2016, 231 (04): : 1067 - 1068
  • [6] Crystal structure of 2-(methylthio)thiazolo[4,5-b]pyridine, C7H6N2S2
    Ren, Yun-Lai
    Tian, Xin-Zhe
    Sun, Yan-Pei
    Liu, Gui-Hua
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2014, 229 (03): : 201 - 202
  • [7] Antioxidant properties of some novel derivatives thiazolo[4,5-b] pyridine
    Chaban, Taras
    Ogurtsov, Volodymyr
    Mahlovanyy, Anatoliy
    Sukhodolska, Natalia
    Chaban, Ihor
    Harkov, Stefan
    Matiychuk, Vasyl
    PHARMACIA, 2019, 66 (04) : 171 - 180
  • [8] Synthesis and Some Properties of 2-(Furan-2-yl)[1,3]thiazolo[4,5-b]pyridine
    A. A. Aleksandrov
    M. M. Elchaninov
    Yu. E. Tarakanova
    D. A. Tishina
    M. L. Shmanovsky
    A. A. Baidin
    Russian Journal of Organic Chemistry, 2021, 57 : 1983 - 1987
  • [9] Synthesis and Some Properties of 2-(Furan-2-yl)[1,3]thiazolo[4,5-b]pyridine
    Aleksandrov, A. A.
    Elchaninov, M. M.
    Tarakanova, Yu E.
    Tishina, D. A.
    Shmanovsky, M. L.
    Baidin, A. A.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 57 (12) : 1983 - 1987
  • [10] Synthesis of 5-Amino-2-oxo-7-aryl-2,3,4,7-tetrahydro-1,3-thiazolo[4,5-b]pyridine-6-carboxamide Derivatives under Microwave Irradiation
    Sun, Hongshun
    Wang, Jianqiang
    Guo, Cheng
    Shen, Linjiang
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2013, 33 (10) : 2220 - 2225