PRESSURE-INDUCED STRIATAL DOPAMINE RELEASE CORRELATES HYPERLOCOMOTOR ACTIVITY IN RATS EXPOSED TO HIGH-PRESSURE

被引：36

作者：

ABRAINI, JH

ROSTAIN, JC

机构：

[1] Lab. biologie/hautes pressions, Faculte de medecine nord, 13326 Marseille, Cedex 15, Blvd. Dramard

来源：

JOURNAL OF APPLIED PHYSIOLOGY | 1991年 / 71卷 / 02期

关键词：

VOLTAMMETRY; STRIATUM; HIGH-PRESSURE NEUROLOGICAL SYNDROME;

D O I：

10.1152/jappl.1991.71.2.638

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Free-moving rats chronically implanted in the striatum with multifiber carbon electrodes selective to dopamine were compressed in a helium-oxygen mixture to 80 bars. Extracellular dopamine level and behavioral symptoms of high-pressure neurological syndrome were simultaneously recorded. Under these conditions, the extracellular level of dopamine monitored by differential pulse voltammetry was found to be pressure dependent, and hyperlocomotor activity, a behavioral symptom of high-pressure neurological syndrome, was found to be linked to these pressure-induced changes in dopamine release.

引用

页码：638 / 643

页数：6

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