PREPARATION OF (6R)-(1R,4R)-6-METHYL-2-(PARA-TOLUENESULFONYL)-5-PHENYLMETHYL-2,5-DIAZABICYCLO[2.2.1]HEPTANES, AND (6S)-(1R,4R)-6-METHYL-2-(PARA-TOLUENESULFONYL)-5-PHENYLMETHYL-2,5-DIAZABICYCLO[2.2.1]HEPTANES, INTERMEDIATES IN A SYNTHESIS OF NEW QUINOLONES

被引：7
|
作者：
REMUZON, P
BOUZARD, D
DUSSY, C
JACQUET, JP
MASSOUDI, M
机构：
[1] Bristol-Myers Squibb, Pharmaceutical Research Institute, 77422 Marne-la-Vallee Cedex 2, B.P.62, Lognes
来源：
HETEROCYCLES | 1992年 / 34卷 / 02期
关键词：
D O I：
10.3987/COM-91-5925
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient chiral synthesis of both diastereoisomers (2a) and (2b) was performed using trans-4-hydroxy-L-proline as starting material. These bridged piperazines were used in the preparation of quinolones.
引用
收藏
页码：241 / 245
页数：5
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