DIETHYL (3-TRIMETHYLSILYL-2-PROPYNYL)PHOSPHONATE, A NEW REAGENT FOR THE PREPARATION OF TERMINAL CONJUGATED ENYNES

被引：0

作者：

GIBSON, AW ^{[1
]}

HUMPHREY, GR ^{[1
]}

KENNEDY, DJ ^{[1
]}

WRIGHT, SHB ^{[1
]}

机构：

[1] MERCK SHARP & DOHME LTD,HERTFORD RD,HODDESDON EN11 9BU,HERTS,ENGLAND

来源：

SYNTHESIS-STUTTGART | 1991年 / 05期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation and use of diethyl (3-trimethylsilyl-2-propynyl)phosphonate as a reactant with aldehydes and ketones for the synthesis of terminal conjugated enynes is reported. The reagent is readily obtained and purified by simple procedures amenable to scale up. The scope of the Horner-Wadsworth-Emmons reaction using the reagent has been briefly explored.

引用

页码：414 / 416

页数：3

共 49 条

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