ANTIHYPERTENSIVE EFFECT OF THE CAPTOPRIL (50 MG) AND HYDROCHLOROTHIAZIDE (25 MG) COMBINATION EVALUATED BY AMBULATORY BLOOD-PRESSURE RECORDING

被引：0

作者：

ASMAR, R ^{[1
]}

BOULANGER, P ^{[1
]}

BENETOS, A ^{[1
]}

DARNE, B ^{[1
]}

LAURENT, S ^{[1
]}

SAFAR, M ^{[1
]}

机构：

[1] LABS THERAPLIX,F-75640 PARIS 13,FRANCE

来源：

PRESSE MEDICALE | 1991年 / 20卷 / 26期

关键词：

ARTERIAL HYPERTENSION; ARTERIAL BLOOD PRESSURE MEASUREMENT;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The anti-hypertensive effects of the captoprilhydrochlorothiazide combination administered during three months as one single morning dose were evaluated in 51 patients with moderate essential hypertension by means of ambulatory blood pressure recording. At the end of the study, the mean values of arterial blood pressure recorded over 24 hours were significantly lowered: systolic pressure was reduced from 145 +/- 11 to 131 +/- 10 mmHg (P < 0.001), and diastolic pressure from 88 +/- 5 mmHg to 81 +/- 4 mmHg (P < 0.001). The same results were recorded during the day (07.00 to 22.00 hours) and during the night (23.00 to 06.00 hours). No change in heart rate was observed.

引用

页码：1215 / 1218

页数：4

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