P-GLYCOPROTEINS IN NEMATODES

被引:0
|
作者
SANGSTER, NC
机构
来源
PARASITOLOGY TODAY | 1994年 / 10卷 / 08期
关键词
D O I
暂无
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The P-glycoprotein (Pgp), a member of a group of integral membrane proteins that contain the ATP-binding cassette, is widely represented in the animal kingdom. A family of Pgp homologues has recently been described in nematodes. Pgps have been implicated in drug resistance in Plasmodium acid in other parasitic protozoa, so the interest of parasitologists now focuses on whether or not they are involved in anthelmintic resistance. Their role in normal cellular functions is also discussed in this article by Nick Sangster.
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页码:319 / 322
页数:4
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