POTASSIUM FLUORIDE-PROMOTED REACTION OF (2-CHLORO-2-NITROETHENYL)BENZENES WITH 1,3-DICARBONYL COMPOUNDS - A GENERAL-SYNTHESIS OF 6,6-DIMETHYL-2-NITRO-3-PHENYL-3,5,6,7-TETRAHYDRO-4(2H)BENZOFURANONES AND SOME ANALOGS

被引：20

作者：

DAUZONNE, D

DEMERSEMAN, P

机构：

[1] Service de Chimie de l'Institut Curie, Section de Biologie, URA 1387P du CNRS, Paris, F 75231

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 06期

关键词：

D O I：

10.1002/jhet.5570270611

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient procedure to prepare in good yields 6,6‐dimethyl‐2‐nitro‐3‐phenyl‐3,5,6,7‐tetrahydro‐4(2H)‐benzofuranones starting from (2‐chloro‐2‐nitroethenyl)benzenes and 5,5‐dimethyl‐1,3‐cyclohexanedione in the presence of potassium fluoride is reported. This method also proved efficient with other 1,3‐dicarbonyl compounds, and has been successfully extended to 1,3‐cyclohexanedione, 2,5‐pentanedione, dibenzoylmethane and ethyl acetoacetate. Copyright © 1990 Journal of Heterocyclic Chemistry

引用

页码：1581 / 1584

页数：4

共 50 条

[21] ALPHA-1-ADRENOCEPTOR REAGENTS - SYNTHESIS OF SOME 5,6,11,11A-TETRAHYDRO-1H-IMIDAZO[1',5'/1,6]PYRIDO AND 5,6,11,11B-TETRAHYDRO-1H-IMIDAZO[1',5'/1,2]PYRIDO[3,4-B]INDOLE-1,3(2H)-DIONES
LOPEZRODRIGUEZ, ML
MORCILLO, MJ
BENHAMU, B
FERNANDEZ, E
SERRANO, J
ORENSANZ, L
CHEMICAL & PHARMACEUTICAL BULLETIN, 1995, 43 (06) : 941 - 946
[22] Synthesis, characterization and Hg(II) Ion selectivity of 1-(2-nitro-4-methyl phenyl)-6-methyl-6-methoxy-1,4,5,6-tetrahydro-pyrimidine-2-(3H)thione (TPT)
Jain, AK
Sondhi, SM
Sharma, VK
ELECTROANALYSIS, 2000, 12 (04) : 301 - 305
[23] Synthesis, characterization and Hg(II) ion selectivity of 1-(2-nitro-4-methyl phenyl)-6-methyl-6-methoxy-1,4,5,6-tetrahydro-pyrimidine-2-(3H)thione (TPT)
Jain, A.K., 2000, Wiley-VCH Verlag (12)
[24] SYNTHESIS OF NOVEL HETEROCYCLES, 2,3,4,11-TETRAHYDRO-3,6-DIHYDROXY-5H-PYRANO[2,3-C][1]BENZOXEPIN-5-ONE AND 4'-(CHLOROMETHYL)-6-HYDROXYSPIRO[1-BENZOXEPIN-3(2H), 2'-[1,3]DIOXOLAN]-5(4H)-ONE
SANGWAN, NK
RASTOGI, SN
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1984, 23 (12): : 1284 - 1285
[25] Synthesis of 6-R-5-aryl-1,3-dioxo-1,2,3,4-tetrahydro-[1]benzothieno[3',2':4,5]pyrido[2,3-d]pyrimidin-5-ium salts and 6-R-5-aryl-5,6-dihydro[1]benzothieno-[3',2':4,5]pyrido[2,3-d]pyrimidine-1,3(2H,4H)-diones
V. S. Tolkunov
A. B. Eresko
A. V. Mazepa
S. V. Tolkunov
Chemistry of Heterocyclic Compounds, 2013, 49 : 941 - 948
[26] Synthesis of 6-R-5-aryl-1,3-dioxo-1,2,3,4-tetrahydro-[1]benzothieno[3',2':4,5]pyrido[2,3-d]pyrimidin-5-ium salts and 6-R-5-aryl-5,6-dihydro[1]benzothieno-[3',2':4,5]pyrido[2,3-d]pyrimidine-1,3(2H,4H)-diones
Tolkunov, V. S.
Eresko, A. B.
Mazepa, A. V.
Tolkunov, S. V.
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2013, 49 (06) : 941 - 948
[27] 6,6-Dimethyl-4,8-dioxospiro[2.5]octane-1,1,2,2-tetracarbonitrile in the synthesis of heterocyclic compounds of the 2,3-dihydrofuran and 5,6,7,8-tetrahydro-4h-chromene series
Kayukova, O.V.
Lukin, P.M.
Kayukov, Ya.S.
Nasakin, O.E.
Khrustalev, V.N.
Nesterov, V.N.
Antipin, M.Yu.
Chemistry of Heterocyclic Compounds, 1998, 34 (02): : 148 - 158
[28] 6,6-Dimethyl-4,8-dioxospiro[2.5]octane-1,1,2,2-tetracarbonitrile in the synthesis of heterocyclic compounds of the 2,3-dihydrofuran and 5,6,7,8-tetrahydro-4h-chromene series
Kayukova O.V.
Lukin P.M.
Kayukov Ya.S.
Nasakin O.E.
Khrustalev V.N.
Nesterov V.N.
Antipin M.Yu.
Chemistry of Heterocyclic Compounds, 1998, 34 (2) : 148 - 158
[29] Synthesis and pharmacological effects of a chimera derivative of tetrahydrocannabinol and phenobarbital, tetrahydro-6,6-dimethyl-9-[5'-phenyl-2',4',6'-(1'H,3'H,5'H)-pyrimidinetrionyl]-3-pentyl-6H-dibenzo[b,d]pyran-ol (TP)
Tateoka, Y
Usami, N
Watanabe, K
Yamamoto, I
RESEARCH COMMUNICATIONS IN ALCOHOL AND SUBSTANCES OF ABUSE, 1996, 17 (3-4): : 151 - 163
[30] SYNTHESIS OF 4,5,6,7-TETRAHYDRO-1(3H)-ISOBENZOFURANONES BY REACTION OF N,N-DIMETHYL-2-LITHIO-1-CYCLOHEXENECARBOXAMIDE WITH ALDEHYDES AND KETONES
BAKER, WR
COATES, RM
JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (06): : 1022 - 1024

← 1 2 3 4 5 →