To study the DNA sequences contacting the nuclear lamina (NL) in vivo, Ehrlich ascites tumor cells were UV-irradiated. The NL was purified, and the DNA fragments covalently linked to the lamina proteins in vivo were cloned and sequenced. Although heterogeneous in length and composition, the sequences displayed homology to the introns and/or flanking regions of different genes, suggesting that functionally distinct regions are organized in a topologically defined manner at the nuclear periphery.
机构:
Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, BeijingKey Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, Beijing
Wen Y.
Gan H.
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Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, BeijingKey Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, Beijing
Gan H.
Shi S.
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Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, BeijingKey Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, Beijing
Shi S.
Jiang Z.
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机构:
Research Institute of Forest Ecology, Environment and Protection, Chinese Academy of Forestry, BeijingKey Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, Beijing
Jiang Z.
Wu L.
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Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, BeijingKey Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, Beijing
Wu L.
Chu J.
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Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, BeijingKey Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration Research Institute of Forestry, Chinese Academy of Forestry, Beijing
机构:
Univ Autonoma Estado Mexico, Fac Med, Lab Biol Mol & Neurociencias, Paseo Tollocan & Jesus Carranza S-N, Toluca 50180, Edo, MexicoUniv Autonoma Estado Mexico, Fac Med, Lab Biol Mol & Neurociencias, Paseo Tollocan & Jesus Carranza S-N, Toluca 50180, Edo, Mexico
Garcia-Vilchis, David
Aranda-Anzaldo, Armando
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Univ Autonoma Estado Mexico, Fac Med, Lab Biol Mol & Neurociencias, Paseo Tollocan & Jesus Carranza S-N, Toluca 50180, Edo, MexicoUniv Autonoma Estado Mexico, Fac Med, Lab Biol Mol & Neurociencias, Paseo Tollocan & Jesus Carranza S-N, Toluca 50180, Edo, Mexico