CHROMATOGRAPHIC AND MASS-SPECTROMETRIC METHODS FOR DETERMINATION OF LYSERGIC-ACID DIETHYLAMIDE (LSD) AND METABOLITES IN BODY-FLUIDS

被引：38
|
作者：
NELSON, CC [1 ]
FOLTZ, RL [1 ]
机构：
[1] NW TOXICOL INC,SALT LAKE CITY,UT 84124
来源：
JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1992年 / 580卷 / 1-2期
关键词：
D O I：
10.1016/0378-4347(92)80530-4
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Continued illicit use of the potent psychedelic drug lysergic acid diethylamide (LSD) has stimulated efforts to develop effective analytical methods for detection of the drug and its metabolites in body fluids from suspected LSD users. Recently reported methods based on gas and liquid chromatography, combined with single- and multiple-stage mass spectral analysis, now permit accurate detection and quantitation of LSD at sub-nanogram/milliliter concentrations.
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页码：97 / 109
页数：13
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