Apoptotic Programmed Cell Death in Cancer and The Modern Methods for Detection of Apoptotic Cells: A Mini Review

被引：0

作者：

Vijayarathna, Soundararajan ^{[1
]}

Kavitha, Nowroji ^{[1
]}

Shanmugapriya ^{[1
]}

Chen, Yeng ^{[2
,3
]}

Kanwar, Jagat R. ^{[4
]}

Sasidharan, Sreenivasan ^{[1
]}

机构：

[1] Univ Sains Malaysia, Inst Res Mol Med INFORMM, Usm 11800, Pulau Pinang, Malaysia

[2] Univ Malaya, Fac Dent, Dent Res & Training Unit, Kuala Lumpur 50603, Malaysia

[3] Univ Malaya, Fac Dent, OCRCC, Kuala Lumpur 50603, Malaysia

[4] Deakin Univ, IFM, Fac Hlth, Sch Med SoM,LIMBR,Nanomed, Waurn Ponds, Vic 3217, Australia

来源：

RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES | 2018年 / 9卷 / 03期

关键词：

apoptotic; cell death; cancer;

D O I：

暂无

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Apoptosis is a process of a programmed cell death in all mammalian cells. Gaining understanding into the modern methods for detection of apoptotic cells will let the development of therapeutic agents with the properties to induced apoptotic cells death in cancer therapy. In this context, modern methods for detection of apoptotic cells play an important role to characterize the dying cells. In the present review, we outline the modern methods that are based on morphological analysis, flow cytometry analysis, cell quantification and mitochondrial membrane potential (Delta psi m) for detection of apoptotic cells death. We also present the basic principle of apoptotic cells death and related latest information in this review.

引用

页码：69 / 76

页数：8

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