Rapid desensitization to isoniazid and rifampin in an adolescent with active pulmonary tuberculosis

被引：1

作者：

Lee, Heirim ^{[1
]}

Kim, Min-Sun ^{[1
]}

Yang, Hea-Kyoung ^{[1
]}

Kim, Minji ^{[1
]}

Lee, Ji Young ^{[1
]}

Kim, Jong-Min ^{[1
]}

Kang, Ji-Man ^{[1
]}

Kim, Yae-Jean ^{[1
]}

Ahn, Kangmo ^{[1
]}

Kim, Jihyun ^{[1
]}

机构：

[1] Sungkyunkwan Univ, Dept Pediat, Samsung Med Ctr, Sch Med, 81 Irwon Ro, Seoul 06351, South Korea

来源：

ALLERGY ASTHMA & RESPIRATORY DISEASE | 2016年 / 4卷 / 03期

关键词：

Immunologic desensitization; Antitubercular agents; Drug hypersensitivity;

D O I：

10.4168/aard.2016.4.3.212

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Hypersensitivity reactions to antituberculosis medicine are obstacles to the treatment of tuberculosis. However, rapid drug desensitization can secure successful treatment with essential antituberculosis medicines in pediatric patients. A 17-year-old boy with active pulmonary tuberculosis complained of generalized erythematous rashes, pruritus on the 11th day of tuberculosis treatment. He was diagnosed with hypersensitivity reactions to isoniazid and rifampin by the oral provocation test. After desensitization, the patient continued to take antituberculosis treatment with isoniazid, rifampin, pyrazinamide, and ethambutol. We report here a case of successful desensitization in an adolescent with hypersensitivity to isoniazid and rifampin.

引用

页码：212 / 216

页数：5

共 50 条

[31] ISONIAZID IN PULMONARY TUBERCULOSIS
不详
BMJ-BRITISH MEDICAL JOURNAL, 1952, 2 (4787): : 764 - 765
[32] Validation of a rapid method for detection of M-tuberculosis resistance to isoniazid and rifampin in Lima, Peru
Solis, LA
Shin, SS
Han, LL
Llanos, F
Stowell, M
Sloutsky, A
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 2005, 9 (07) : 760 - 764
[33] Prospective evaluation of pyrosequencing for the rapid detection of isoniazid and rifampin resistance in clinical Mycobacterium tuberculosis isolates
Marttila, H. J.
Makinen, J.
Marjamaki, M.
Soini, H.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2009, 28 (01) : 33 - 38
[34] Development of a pyrosequencing approach for rapid screening of rifampin, isoniazid and ethambutol-resistant Mycobacterium tuberculosis
Zhao, JR
Bai, YJ
Wang, Y
Zhang, QH
Luo, M
Yan, XJ
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 2005, 9 (03) : 328 - 332
[35] Rapid and accurate detection of rifampin and isoniazid-resistant Mycobacterium tuberculosis using an oligonucleotide array
Huang, W. -L.
Hsu, Z. -J.
Chang, T. C.
Jou, R.
CLINICAL MICROBIOLOGY AND INFECTION, 2014, 20 (09) : O542 - O549
[36] Evaluation of the genotype MTBDR assay for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis isolates
Cavusoglu, Cengiz
Turhan, Ajda
Akinci, Pinar
Soyler, Ilknur
JOURNAL OF CLINICAL MICROBIOLOGY, 2006, 44 (07) : 2338 - 2342
[37] Prospective evaluation of pyrosequencing for the rapid detection of isoniazid and rifampin resistance in clinical Mycobacterium tuberculosis isolates
H. J. Marttila
J. Mäkinen
M. Marjamäki
H. Soini
European Journal of Clinical Microbiology & Infectious Diseases, 2009, 28 : 33 - 38
[38] Emergence and selection of isoniazid and rifampin resistance in tuberculosis granulomas
Pienaarl, Elsje
Linderman, Jennifer J.
Kirschner, Denise E.
PLOS ONE, 2018, 13 (05):
[39] OBSERVATIONS ON SHORT COURSE, LARGELY TWICE WEEKLY CHEMOTHERAPY WITH ISONIAZID-RIFAMPIN FOR PULMONARY TUBERCULOSIS
DUTT, AK
JONES, L
STEAD, WW
CHEST, 1978, 74 (03) : 336 - 336
[40] Isoniazid, Rifampin, and Pyrazinamide Plasma Concentrations in Relation to Treatment Response in Indonesian Pulmonary Tuberculosis Patients
Burhan, Erlina
Ruesen, Carolien
Ruslami, Rovina
Ginanjar, Arum
Mangunnegoro, Hadiarto
Ascobat, Purwantyastuti
Donders, Rogier
van Crevel, Reinout
Aarnoutse, Rob
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 57 (08) : 3614 - 3619

← 1 2 3 4 5 →