EVALUATION OF CORRELATION OF SERUM PROGESTERONE LEVEL WITH PREGNANCY OCCURRENCE IN FROZEN EMBRYO TRANSFER

BACKGROUND Progesterone is an endogenous hormone secreted by ovaries that prepares uterine endometrium for implantation. The aim of this study was to evaluate the relation of serum progesterone level on the day of transferring frozen embryo with pregnancy occurrence. MATERIALS AND METHODS 161 women were chosen for frozen embryo transfer. From the second day of their cycle, they were treated with 2 mg per 8 hours estradiol. From the 13th day, 5 mg intramuscular (IM) progesterone was injected every 12 hours to increase endometrium thickness above 8 mm. 4 days after progesterone administration, embryo transfer was performed, and progesterone level was measured. Pregnancy occurrence was also evaluated. RESULTS The average progesterone level in 25 women with positive beta HCG was 26.26 +/- 8.58 on 1st day, 26.63 +/- 8.22 on 17th day and 24.3 +/- 11.48 on the 18th day of transfer. In 136 non-pregnant women it was 25.61 +/- 16.01 on 1st day, 29.03 +/- 14.45 on 17th day and 15.42 +/- 2.77 on 18th day. CONCLUSION There was no relationship between serum level of progesterone on the day of transfer and pregnancy occurrence.