TREATMENT OF GASTRIC-ULCER - SUCRALFATE VS FAMOTIDINE

被引：0
|
作者：
HOFFENBERG, P [1 ]
REYES, V [1 ]
PALMA, J [1 ]
OSSA, P [1 ]
MAGGIOLO, P [1 ]
KLINGER, J [1 ]
机构：
[1] HOSP SALVADOR,SANTIAGO,CHILE
来源：
REVISTA MEDICA DE CHILE | 1991年 / 119卷 / 01期
关键词：
PEPTIC ULCER; STOMACH; DRUG THERAPY; SUCRALFATE; FAMOTIDINE; CLINICAL TRIALS;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We conducted a double blind random study on 79 patients with gastric ulcer: 39 received sucralfate, 1 g 4 times day (Group 1) and 40 received a single evening dose of famotidine, 40 mg (Group 2). At 4 weeks, endoscopy revealed healing of the ulcer in 46% of patients in Group 1 and 40% in Group 2 (NS). At 8 weeks, corresponding figures were 90% and 75% (NS). All patients were able to complete treatment and minor side effects were reported from all patients, 36% with sucralfate and 28% with famotidine. Thus, sucralfate and famotidine are equally effective for therapy of gastric ulcer. The higher percentage of healing with sucralfate observed in this study was not statistically significant.
引用
收藏
页码：45 / 49
页数：5
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