AROMATIC NUCLEOPHILIC-SUBSTITUTION ON THIOPHENE RINGS

被引：15
|
作者：
ELKASSMI, A [1 ]
HERAUD, G [1 ]
BUCHNER, W [1 ]
FACHE, F [1 ]
LEMAIRE, M [1 ]
机构：
[1] UNIV LYON 1,ECOLE SUPER CHIM IND LYON,CATALYSE & SYNTHESE ORGAN LAB,CNRS,F-69622 VILLEURBANNE,FRANCE
来源：
JOURNAL OF MOLECULAR CATALYSIS | 1992年 / 72卷 / 03期
关键词：
D O I：
10.1016/0304-5102(92)85007-3
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
A new method for the aromatic nucleophilic substitution is described here with the synthesis of 3-substituted thiophenes having polyfluorinated alkoxygroups. Different catalysts and bases were tested and the best results were obtained with Cul and NaH. DMF or DME was used as solvent and yields of 60 to 70% of pure isolated product were obtained, depending on the polyfluorinated chain.
引用
收藏
页码：299 / 305
页数：7
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