A DISINTEGRATION TEST FOR VAGINAL TABLETS - COMPARISON WITH BP TEST

被引:4
|
作者
YAMAGUCHI, M
TANNO, K
SUGIBAYASHI, K
MORIMOTO, Y
机构
[1] NIIGATA UNIV HOSP,DEPT PHARM,NIIGATA 951,JAPAN
[2] JOSAI UNIV,FAC PHARMACEUT SCI,SAKADO,SAITAMA 35002,JAPAN
关键词
D O I
10.1111/j.2042-7158.1990.tb07023.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Abstract— To improve the disintegration test for vaginal tablets described in the British Pharmacopoeia (BP), a monitoring apparatus was added, and tested with seven effervescent and five non‐effervescent tablets. A tablet was placed on the metal disc of the BP disintegration apparatus, and the guided plate was placed on the tablet. The guided plate moved downward smoothly in a cylinder as the tablet disintegrated. The movement was recorded by using a kymograph. The end‐point and process of disintegration of the tablet were automatically recorded and the results obtained suggest that the modified test is a useful tool for the quality control of vaginal tablets. 1990 Royal Pharmaceutical Society of Great Britain
引用
收藏
页码:795 / 796
页数:2
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