SYNTHESIS OF 6-ALKOXY-3-ARYL-6-TRIMETHYLSILYLOXY-5,6-DIHYDRO-4H-1,2-OXAZINES AND THEIR ACID-CATALYZED HYDROLYSIS LEADING TO 3-ARYL-5,6-DIHYDRO-4H-1,2-OXAZIN-6-ONES AND OR 4-ARYL-4-(HYDROXYIMINO)BUTYRIC ACID-ESTERS

被引：6

作者：

TANIMOTO, S

MATSUMOTO, H

HOJO, M

TOSHIMITSU, A

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 12期

关键词：

D O I：

10.1039/p19910003153

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cycloaddition of alpha-nitrosostyrene and its ring-substituted derivatives, which are generated by the reaction of alpha-chloroacetophenone oxime and its ring-substituted derivatives with K2CO3 in tetrahydrofuran, with ketene trimethylsilyl acetals proceeds to afford 6-alkoxy-3-aryl-6-trimethylsilyloxy-5,6-dihydro-4H-1,2-oxazines. These oxazines are susceptible to hydrochloric acid-catalysed hydrolysis affording 3-aryl-5,6-dihydro-4H-1,2-oxazin-6-one and/or 4-aryl-4-(hydroxyimino)butyric acid esters.

引用

页码：3153 / 3157

页数：5

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