TISSUE LACTATE IN PEDIATRIC HEAD TRAUMA - A CLINICAL-STUDY USING H-1-NMR SPECTROSCOPY

被引：31

作者：

SUTTON, LN ^{[1
]}

WANG, Z ^{[1
]}

DUHAIME, AC ^{[1
]}

COSTARINO, D ^{[1
]}

SAUTER, R ^{[1
]}

ZIMMERMAN, R ^{[1
]}

机构：

[1] SIEMENS MED SYST INC,PHILADELPHIA,PA

来源：

PEDIATRIC NEUROSURGERY | 1995年 / 22卷 / 02期

关键词：

LACTATE; SPECTROSCOPY; HEAD INJURY;

D O I：

10.1159/000120881

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In order to define the metabolic abnormalities associated with different types of pediatric head injury, proton magnetic resonance spectroscopy was performed on 21 cerebral regions obtained from 17 patients. On the basis of MRI scans, the regions of interest were classified as normal (6 hemispheres), or showing diffuse axonal injury (3 hemispheres), contusion (4 hemispheres), or cerebral infarction (8 hemispheres). In comparison with normal brain there was no significant elevation in tissue lactate in the diffuse axonal injury patients, but a significant increase in the regions of contusion and infarction. It is concluded that treatment strategies using buffering agents are most likely to benefit these two groups of patients.

引用

页码：81 / 87

页数：7

共 20 条

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[2]

Berry I, 1986, Acta Radiol Suppl, V369, P338

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