SIMPLE DETERMINATION OF TIN IN BIOLOGICAL-MATERIALS BY ATOMIC-ABSORPTION SPECTROMETRY WITH A GRAPHITE-FURNACE

A simple and rapid determination of tin in biological materials (blood, brain, liver, kidney, etc,) by atomic absorption spectrometry (AAS) with a graphite furnace is described. Suppression of interferences by direct addition of ascorbic acid in wet-ashed biological materials was investigated for the determination of tin. This method involves no extraction with organic solvent for removal of the interferences, and therefore it is neither time consuming nor error prone, and is suitable for large sample sizes and small sample volumes. The limit of detection of this method is 0.002-mu-g/mL, equivalent to a limit of detection in the materials of 0.02-mu-g/g. The calibration graph is linear up to 1-mu-g/mL of tin.