DOES A CENTRALIZED CLOCK FOR AGING EXIST

被引:0
|
作者
KLOEDEN, PE
ROSSLER, R
ROSSLER, OE
机构
[1] UNIV TUBINGEN,MED POLICLIN,W-7400 TUBINGEN 1,GERMANY
[2] UNIV TUBINGEN,INST PHYS & THEORET CHEM,W-7400 TUBINGEN 1,GERMANY
[3] MURDOCH UNIV,SCH MATH & PHYS SCI,MURDOCH,WA 6150,AUSTRALIA
关键词
LIFE EXPECTANCY CURVES; PROGRAMMED THEORY OF AGING; ZEITGEBER; PINEAL CALCIFICATION; MELATONIN FLUCTUATIONS; EXPERIMENTAL VERIFICATION;
D O I
暂无
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
It is proposed that a centralized clock controlling ageing is located in the pineal gland with the calcification process occurring there providing a highly accurate bio-inorganic timing mechanism and the secreted melatonin carrying a signal to all cells in the organism. An explicit programme of data gathering and experiments suitable for the falsification of the proposal, which is consistent with presently known anatomical and physiological facts, is presented. The underlying motivation comes from evolutionary biology and the invariance, that is the allometry, of life expectancy curves.
引用
收藏
页码:314 / 322
页数:9
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