DEMONSTRATION OF BAEYER-VILLIGER OXIDATION AND THE COURSE OF CYCLIZATION IN BISFURAN RING FORMATION DURING AFLATOXIN-B1 BIOSYNTHESIS

被引：23
|
作者：
MCGUIRE, SM [1 ]
TOWNSEND, CA [1 ]
机构：
[1] JOHNS HOPKINS UNIV,DEPT CHEM,BALTIMORE,MD 21218
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 04期
关键词：
D O I：
10.1016/S0960-894X(01)81247-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The mechanism of tetrahydrobisfuran formation in aflatoxin B1 biosynthesis is defined in experiments that monitor the incorporation of molecular oxygen into an anthraquinone intermediate of the pathway in conjunction with cell-free reactions that complete the synthesis of the tetrahydrobisfuran present in versicolorin B wherein the second ring bears the labeled oxygen.
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页码：653 / 656
页数：4
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