THE EFFECTS OF ICI-D1542, A THROMBOXANE A2 SYNTHASE INHIBITOR AND TP RECEPTOR ANTAGONIST, ON COLLAGEN-INDUCED HUMAN PLATELET DEGRANULATION AND AGGREGATION

被引:0
|
作者
MENYS, VC [1 ]
机构
[1] MANCHESTER POLYTECH,DEPT BIOL SCI,MANCHESTER M1 5GD,LANCS,ENGLAND
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:P130 / P130
页数:1
相关论文
共 28 条
  • [1] ICI-D1542 - A POTENT THROMBOXANE A2 (TXA2) SYNTHASE INHIBITOR AND RECEPTOR ANTAGONIST
    BROWNRIGG, N
    GARCIA, R
    JESSUP, R
    LEE, V
    TUNSTALL, S
    WAYNE, M
    BRITISH JOURNAL OF PHARMACOLOGY, 1992, 107 : P129 - P129
  • [2] Effects of BM-573, a dual thromboxane A2 receptor antagonist and thromboxane synthase inhibitor, on osteogenic sarcoma cell-induced platelet aggregation.
    de Leval, X
    David, JL
    Neven, P
    Benoit, V
    Pirotte, B
    Merville, MP
    Bours, V
    Dogné, JM
    BLOOD, 2001, 98 (11) : 43B - 43B
  • [3] EV-077-3201-2TBS, a reversible dual thromboxane receptor antagonist and thromboxane synthase inhibitor, is more potent than aspirin in inhibiting arachidonic acid and collagen-induced human platelet aggregation in vitro
    Alberts, P.
    Fontana, P.
    Sakariassen, K. S.
    Bounameaux, H.
    Meyer, J. P.
    Sorensen, Santana A.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 : 968 - 968
  • [4] Effects of cysteinyl-leukotriene receptor antagonist, thromboxane A2 receptor antagonist, and thromboxane A2 synthetase inhibitor on antigen-induced bronchoconstriction in patients with asthma
    Obase, Y
    Shimoda, T
    Matsuo, N
    Matsuse, H
    Asai, S
    Kohno, S
    CHEST, 1998, 114 (04) : 1028 - 1032
  • [5] Activity of a novel dual thromboxane A2 receptor antagonist and thromboxane synthase inhibitor (BM-573) on platelet function and isolated smooth muscles
    Rolin, S
    Dogné, JM
    Michaux, C
    Delarge, J
    Masereel, B
    PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 2001, 65 (02): : 67 - 72
  • [6] FORMATION OF PGD2 CONTRIBUTES TO THE ANTI-AGGREGATORY EFFICACY OF ZD1542, A THROMBOXANE-A2 SYNTHASE INHIBITOR AND TP RECEPTOR ANTAGONIST, IN HUMAN WHOLE-BLOOD
    MENYS, VC
    PLATELETS, 1994, 5 (03) : 156 - 161
  • [7] The roles Of αIIbβ3-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation
    Cho, MJ
    Liu, JL
    Pestina, TI
    Steward, SA
    Thomas, DW
    Coffman, TM
    Wang, DM
    Jackson, CW
    Gartner, TK
    BLOOD, 2003, 101 (07) : 2646 - 2651
  • [8] INVITRO AND EXVIVO EFFECTS OF PICOTAMIDE, A COMBINED THROMBOXANE-A2-SYNTHASE INHIBITOR AND THROMBOXANE-A2-RECEPTOR ANTAGONIST, ON HUMAN PLATELETS
    BERRETTINI, M
    DECUNTO, M
    PARISE, P
    GRASSELLI, S
    NENCI, GG
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1990, 39 (05) : 495 - 500
  • [9] Effects of the dual TP receptor antagonist and thromboxane synthase inhibitor EV-077 on human endothelial and vascular smooth muscle cells
    Petri, Marcelo H.
    Tellier, Celine
    Michiels, Carine
    Ellertsen, Ingvill
    Dogne, Jean-Michel
    Back, Magnus
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 441 (02) : 393 - 398
  • [10] Inhibitory Effects of Resveratrol on Platelet Activation Induced by Thromboxane A2 Receptor Agonist in Human Platelets
    Yang, Yumin
    Wang, Xiaoling
    Zhang, Li
    An, Huiping
    Zao, Zhigao
    AMERICAN JOURNAL OF CHINESE MEDICINE, 2011, 39 (01): : 145 - 159