INHERITANCE OF PREDISPOSITION TO CATALEPSY IN MICE

被引：47
|
作者：
KULIKOV, AV
KOZLACHKOVA, EY
MASLOVA, GB
POPOVA, NK
机构：
[1] Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, Novosibirsk
来源：
BEHAVIOR GENETICS | 1993年 / 23卷 / 04期
关键词：
INBRED MICE; CATALEPSY; INTERSTRAIN DIFFERENCES; MENDELIAN ANALYSIS; MONOGENIC INHERITANCE;
D O I：
10.1007/BF01067439
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
''Pinch-induced'' catalepsy (excessive freezing) was studied in mice of nine inbred strains. The CBA/Icg strain had the highest predisposition to catalepsy, with 56% males and 73% females exhibiting 120-s immobility after four tests. A Mendelian analysis of predisposition to catalepsy was performed on CBA/Icg and AKR/J mice contrasting in this trait. Reciprocal F1 hybrids did not display freezing after 10 tests. The number of cataleptic and noncataleptic animals among the F2's and in the families of the CBA x F2 backcrosses agreed with the hypothesis that the pronounced predisposition to catalepsy in the CBA/Icg mice was determined by a single autosomal locus in homozygous recessive condition.
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收藏
页码：379 / 384
页数：6
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