2 '-[(4-Fluorophenyl)carbony1]-1 '-pheny1-1 ',2 ',5 ',6 ',7',7a '- hexahydrospiro[indole-3,3 '-pyrrolizin]-2(1H)-one

被引：1

作者：

Sapnakumari, Majal ^{[1
]}

Narayana, Badiadka ^{[1
]}

Samshuddin, Seranthimata ^{[1
]}

Sarojini, Balladka Kunhanna ^{[2
]}

机构：

[1] Mangalore Univ, Dept Studies Chem, Mangalagangothri 574199, Karnataka, India

[2] PA Coll Engn, Dept Chem Res, Mangalore 574153, Karnataka, India

来源：

MOLBANK | 2013年 / 02期

关键词：

spiro[indole-3,3'-pyrrolizine; 1-(4-fluoropheny1)-3-phenylprop-2-en-l-one isatin; L-proline; reducing power assay;

D O I：

10.3390/M802

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new spiro[indole-3,3'-pyrrolizine] derivative is regioselectively synthesized by the straightforward multicomponent reaction of 1-(4-fluorophenyl)-3-phenylprop-2-en1-one, isatin and L-proline without any catalyst. The structure of the newly synthesized compound is characterized by IR, NMR, UV -visible and mass spectral data. The compound is also screened for its reducing power assay.

引用

页码：1 / 5

页数：5

共 50 条

[1] Synthesis, characterization, biological evaluation and docking studies of 2′-[(2",4"-difluorobiphenyl-4-yl)carbonyl]-1′-aryl-1′,2′,5′,6′,7′,7a′-hexahydrospiro[indole-3,3′-pyrrolizin]-2(1H)-ones
Fathimunnisa, M.
Manikandan, H.
Neelakandan, K.
Prasad, N. Rajendra
Selvanayagam, S.
Sridhar, B.
JOURNAL OF MOLECULAR STRUCTURE, 2016, 1122 : 205 - 218
[2] 3-(4-fluorophenyl)-1-[1′-(4-fluorophenyl)2-oxo-5′,6′,7′,7a′-tetrahydro-1H-indole-3(2H)-spiro-3′(2′H)-1H′-pyrrolizin-2′-yl]prop-2-en-1-one
Nirmala, S.
Murugan, R.
Kamala, E. Theboral Sugi
Sudha, L.
Narayanan, S. Sriman
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1774 - U2105
[3] Crystal structures of 2 '-benzoyl-1 '-(4-methylphenyl)-1,1 ',2,2 ',5 ',6 ',7 ',7a '-octahydrospiro [indole3,3 '-pyrrolizin]-2-one and 2 '-(4-bromobenzoyl)-1 '(2-chlorophenyl)-1,1 ',2,2 ',5 ',6 ',7 ',7a '-octahydrospiro [indole-3,3 '-pyrrolizin]-2-one
Chandrarekha, M.
Srinivasan, N.
Vijaya, P. Kottala
Siva, A.
Krishnakumar, R. V.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2016, 72 : 1637 - +
[4] Crystal structure of 2 '-[(2 ',4 '-difluorobipheny1-4yl)carbonyl]-1 '-phenyl-1 ',2 ',5 ',6 ',7 ',7a '-hexahydro- spiro[indole-3 3 '-pyrrolizin]-2(1H)-one
Fathimunnisa, M.
Manikandan, H.
Selvanayagam, S.
Sridhar, B.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2015, 71 : 915 - +
[5] 1′,5-Dinitro-2′-phenyl-2′,3′,5′,6′,7′,7a′-hexahydrospiro[indoline-3,3′-1′H-pyrrolizin]2-one
Sarrafi, Yaghoub
Alimohammadi, Kamal
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1740 - U1785
[6] 2′-Hydroxymethyl-1′-(4-methylphenyl)-2′-nitro-1′,2′,5′,6′,7′,7a′-hexahydrospiro[indoline-3,3′-pyrrolizin]-2-one
Sathya, S.
Bhaskaran, Sundari
Usha, G.
Sivakumar, N.
Bakthadoss, M.
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2012, 68 : O277 - U1615
[7] 2′-Methyl-2′-nitro-1′-phenyl-2′,3′,5′,6′,7′,7a′-hexahydrospiro[indoline-3,3′-1′H-pyrrolizin]-2-one
Sarrafi, Yaghoub
Alimohammadi, Kamal
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1490 - U2281
[8] Crystal structure of (5"E)-1"-benzyl-5"-(4-fluorobenzylidene)-1′-(4-fluorophenyl)-5′,6′,7′,7a′-tetrahydro-1′H,4"H-dispiro[indole-3,3′-pyrrolizine-2′,3"]-2,4"(1H)-dione, C38H33F2N3O2
Li, Guobin
Liu, Bin
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2010, 225 (01): : 113 - 114
[9] Synthesis, characterization, antibacterial activity and cytotoxicity of (1′R,2′S,7a′S)-2′-(2,5-dichlorothiophene-3-carbonyl)-1′-(aryl)-1′,2′,5′,6′,7′,7a′-hexahydrospiro[indoline-3,3′-pyrrolizin]-2-one derivatives
Al-Refai, Mahmoud
Ali, Basem F.
Al-Masri, Eman K.
Mansi, Iman A.
Aljaar, Nayyef
Abu-Irmaileh, Bashaer
Geyer, Armin
Ivlev, Sergei I.
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2023, 60 (12) : 2009 - 2022
[10] Crystal Structure and Molecular Docking Studies of 1-Ethyl-2′-(furan-2-carbonyl)-1′-(furan-2-yl)-1′,2′,5′,6′,7′,7a′-hexahydrospiro[indoline-3,3′-pyrrolizin]-2-one
Venkata Bharat Nishtala
Srinivas Basavoju
Journal of Chemical Crystallography, 2018, 48 : 78 - 90

← 1 2 3 4 5 →