ANTIVITAMIN MECHANISM IN REALIZATION OF HYDROXYTHIAMINE ACTION ON PROTEIN AND RNA BIOSYNTHESIS IN RAT-LIVER

被引：0
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作者：
FUSTOCHENKO, BP
KHOKHA, AM
OSTROVSKY, YM
机构：
来源：
DOKLADY AKADEMII NAUK BELARUSI | 1990年 / 34卷 / 11期
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中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Simultaneous administration of vitamin B1 with its derivative hydroxythiamine results in cessation of antivitamin action on the protein and RNA biosynthesis in rat liver. Because of this and also of the absence of any changes in the plasma corticosterone level and concurrent hydroxythiamine-induced inhibition of RNA synthesis in the rats, it is possible to consider the antivitamin effect, realized via vitamin-dependent reactions, to be the key factor in the influence of hydroxythiamine on the protein and RNA biosynthesis.
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页码：1046 / 1048
页数：3
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