DETERMINATION OF IVERMECTIN RESIDUES IN SWINE TISSUES - AN IMPROVED CLEANUP PROCEDURE USING SOLID-PHASE EXTRACTION

被引：33
|
作者：
NORDLANDER, I
JOHNSSON, H
机构：
[1] Nutrition Laboratory, National Food Administration, Uppsala, S-751 26
来源：
FOOD ADDITIVES AND CONTAMINANTS | 1990年 / 7卷 / 01期
关键词：
HPLC-fluorescence detection; Ivermectin; Swine muscle tissue;
D O I：
10.1080/02652039009373823
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A rapid and sensitive HPLC method has been developed for the determination of ivermectin in swine tissues. The clean-up procedure is based on solid-phase extraction on a Bond-Elut C8 cartridge. The average recovery from spiked swine muscle tissue was 87% in the concentration range 2-20 μg/kg. The method has a limit of detection of 0.5-1 μg/kg. A survey of the levels in muscle tissues from 35 sanitary slaughtered sows was made. Five samples were found to contain ivermectin at concentrations between 3.4 and 27.6 μg/kg. A good correlation (r = 0.9696) was found between these results and those obtained using another established method. © 1990 Taylor & Francis Group, LLC.
引用
收藏
页码：79 / 82
页数：4
相关论文
共 50 条
  • [1] Solid-Phase Extraction Cleanup for Ivermectin in Liver Tissue
    Reising, Kyle P.
    Di, Benedetto, Neffer Migdal
    1998, AOAC International (81)
  • [2] Solid-phase extraction cleanup for ivermectin in liver tissue
    Reising, KP
    Di Benedetto, NM
    JOURNAL OF AOAC INTERNATIONAL, 1998, 81 (02) : 484 - 487
  • [3] DETERMINATION OF CLORSULON RESIDUES IN MILK USING A SOLID-PHASE EXTRACTION CLEANUP AND LIQUID-CHROMATOGRAPHIC DETERMINATION
    SCHENCK, FJ
    WAGNER, R
    BARGO, W
    JOURNAL OF LIQUID CHROMATOGRAPHY, 1993, 16 (02): : 513 - 520
  • [4] Determination of Menbutone Residues in Edible Swine Tissues Based on Solid-Phase Extraction and RP-HPLC
    Zhou, Liya
    Zhang, Ping
    Liu, Jiangbo
    Wu, Xiaobo
    Luo, Lei
    Xu, Xingran
    Luo, Yonghuang
    CURRENT PHARMACEUTICAL ANALYSIS, 2020, 16 (02) : 159 - 167
  • [5] Use of automated solid-phase extraction equipment for the determination of ivermectin residues in animal liver by HPLC
    Scarano, G
    Esposito, H
    Grasso, L
    Soprano, V
    Oliviero, G
    ANALYST, 1998, 123 (12) : 2551 - 2553
  • [6] Sample Cleanup Using Solid-Phase Dispersive Extraction for Determination of Vancomycin in Serum
    Yasuhiro Sakamoto
    Yuki Jinno
    Ikumi Shinodzuka
    Yusuke Iwasaki
    Rie Ito
    Koichi Saito
    Analytical Sciences, 2014, 30 : 271 - 275
  • [7] Sample Cleanup Using Solid-Phase Dispersive Extraction for Determination of Vancomycin in Serum
    Sakamoto, Yasuhiro
    Jinno, Yuki
    Shinodzuka, Ikumi
    Iwasaki, Yusuke
    Ito, Rie
    Saito, Koichi
    ANALYTICAL SCIENCES, 2014, 30 (02) : 271 - 275
  • [8] Determination of organochlorine and organophosphorus pesticide residues in eggs using a solid phase extraction cleanup
    Schenck, FJ
    Donoghue, DJ
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2000, 48 (12) : 6412 - 6415
  • [9] Determination of organochlorine pesticide and polychlorinated biphenyl residues in fatty fish by tandem solid-phase extraction cleanup
    Schenck, FJ
    Calderon, L
    Podhorniak, LV
    JOURNAL OF AOAC INTERNATIONAL, 1996, 79 (05) : 1209 - 1214
  • [10] Florisil solid-phase extraction cartridges for cleanup of organochlorine pesticide residues in foods
    Schenck, FJ
    Calderon, L
    Saudarg, DE
    JOURNAL OF AOAC INTERNATIONAL, 1996, 79 (06) : 1454 - 1458
12345