A PHYSICAL MAP OF A 1.3-MB REGION ON THE LONG ARM OF CHROMOSOME-12, SPANNING THE GLI AND LRP LOCI

被引：20
|
作者：
FORUS, A [1 ]
MYKLEBOST, O [1 ]
机构：
[1] NORWEGIAN RADIUM HOSP,INST CANC RES,DEPT TUMOR BIOL,N-0310 OSLO,NORWAY
来源：
GENOMICS | 1992年 / 14卷 / 01期
关键词：
D O I：
10.1016/S0888-7543(05)80292-7
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
We have used pulsed-field gel electrophoresis to construct a long-range restriction map spanning more than 1.3 million bp of the q13-q14 segment of chromosome 12. Within this region lie the genes coding for the gli oncogene and the low-density lipoprotein receptor-related protein (LRP). The distance between the genes is about 200-300 kb. We also observe a methylation-free island 3′ to the LRP gene. © 1992 Academic Press, Inc. All rights reserved.
引用
收藏
页码：117 / 120
页数：4
相关论文
共 18 条
  • [1] A RADIATION HYBRID MAP WITH 60 LOCI COVERING THE ENTIRE SHORT ARM OF CHROMOSOME-12
    RAEYMAEKERS, P
    VANZAND, K
    JUN, L
    HOGLUND, M
    CASSIMAN, JJ
    VANDENBERGHE, H
    MARYNEN, P
    GENOMICS, 1995, 29 (01) : 170 - 178
  • [2] A PHYSICAL MAP OF THE REGION SPANNING THE CHROMOSOME-12 TRANSLOCATION BREAKPOINT IN A MESOTHELIOMA WITH A T(X-12)(Q22-P13)
    AERSSENS, J
    GUO, C
    VERMEESCH, J
    BAENS, M
    BROWNE, D
    LITT, M
    VANDENBERGHE, H
    MARYNEN, P
    CYTOGENETICS AND CELL GENETICS, 1995, 71 (03): : 268 - 275
  • [3] GENETIC AND PHYSICAL MAP OF THE SPINOCEREBELLAR ATAXIA-2 (SCA2) REGION ON HUMAN CHROMOSOME-12
    PULST, SM
    NECHIPORUK, A
    NECHIPORUK, T
    LOPESCENDES, T
    ROULEAU, GA
    KORT, E
    DEJONG, P
    WEISSENBACH, J
    CHUMAKOV, I
    NEUROLOGY, 1995, 45 (04) : A422 - A422
  • [4] A PHYSICAL MAP OF 14 GENE LOCI ON THE DISTAL PORTION OF THE LONG ARM OF HUMAN CHROMOSOME-5
    WARRINGTON, JA
    HALL, LV
    HINTON, LM
    MILLER, JN
    LOVETT, M
    WASMUTH, JJ
    CYTOGENETICS AND CELL GENETICS, 1991, 58 (3-4): : 1905 - 1905
  • [5] PHYSICAL AND TRANSCRIPTION MAP OF A 2.5 MB REGION OF HUMAN-CHROMOSOME 9Q34 SPANNING THE TUBEROUS SCLEROSIS COMPLEX-1 CANDIDATE REGION
    MURRELL, J
    CUTONE, S
    VU, D
    RUTTER, M
    LONG, K
    LAWRENCE, N
    STOTLER, C
    MCCORMICK, MK
    BUCKLER, A
    AMERICAN JOURNAL OF HUMAN GENETICS, 1995, 57 (04) : 1542 - 1542
  • [6] Fine physical and transcript mapping of a 1.8 Mb region spanning the locus for childhood acute lymphoblastic leukemia on chromosome 12p12.3
    Aïssani, B
    Sinnett, D
    GENE, 1999, 240 (02) : 297 - 305
  • [7] A 6-MB YEAST ARTIFICIAL CHROMOSOME CONTIG AND LONG-RANGE PHYSICAL MAP ENCOMPASSING THE REGION ON CHROMOSOME 12Q15 FREQUENTLY REARRANGED IN A VARIETY OF BENIGN SOLID TUMORS
    SCHOENMAKERS, EFPM
    GEURTS, JMW
    KOOLS, PFJ
    MOLS, R
    HUYSMANS, C
    BULLERDIEK, J
    VANDENBERGHE, H
    VANDEVEN, WJM
    GENOMICS, 1995, 29 (03) : 665 - 678
  • [8] A LONG-RANGE RESTRICTION MAP SPANNING THE MYXOID LIPOSARCOMA BREAKPOINT IN THE Q13-14 REGION OF HUMAN-CHROMOSOME-12
    FORUS, A
    KOOLS, PFJ
    SCHOENMAKERS, EFPM
    VANDEVEN, WJM
    MYKLEBOST, O
    HUMAN GENETICS, 1994, 94 (03) : 259 - 264
  • [9] Physical and transcript map of the autosomal dominant colobomatous microphthalmia locus on chromosome 15q12-q15 and refinement to a 4.4 Mb region
    Michon, L
    Morlé, L
    Bozon, M
    Duret, L
    Zech, JC
    Godet, J
    Plauchu, H
    Edery, P
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2004, 12 (07) : 574 - 578
  • [10] Physical and transcript map of the autosomal dominant colobomatous microphthalmia locus on chromosome 15q12-q15 and refinement to a 3.4 Mb region
    Michon, L
    Morle, L
    Bozon, M
    Duret, L
    Zech, JC
    Godet, J
    Plauchu, H
    Edery, P
    AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 73 (05) : 438 - 438
12