Protective Effect of Livina, A Polyherbal Liquid Formulation Against Ethanol Induced Liver Damage In Rats

Alcohol liver disease (ALD) is a major health problem worldwide. After heart disease and cancer, alcoholism is the world's biggest health problem and most deaths attributed to alcoholism are caused by cirrhosis of the liver. Results show that T.TVINA, a poly herbal liquid formulation was effective in blunting ethanol-induced enhanced activities of serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), level of serum bilirubin (both total and direct), blood urea nitrogen (BUN), serum total cholesterol, liver weight loss and was also effective in reducing ethanolinduced lipid peroxidation. Results of hepatocellular damage caused by ethanol and its recovery by T.TVINA, suggest that it might be considered as apotential source of natural hepatoprotective agent..