XENIAFARAUNOL-A AND XENIAFARAUNOL-B, AND FARAUNATIN - 3 NEW CYTOTOXIC DITERPENES FROM THE SOFT CORAL XENIA-FARAUNENSIS

被引：16
|
作者：
KASHMAN, Y [1 ]
SALTOUN, M [1 ]
RUDI, A [1 ]
BENAYAHU, Y [1 ]
机构：
[1] TEL AVIV UNIV,DEPT ZOOL,IL-69978 TEL AVIV,ISRAEL
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 47期
关键词：
D O I：
10.1016/S0040-4039(00)78516-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The organic extract of Xenia faraunensis was found to contain besides xeniolide A and B three novel diterpenes: xeniafaraunol A (1), -B (2) and faraunatin (3). The structure of compounds 1-3 was defined by spectral methods and mainly 1D and 2D NMR experiments. Xeniafaraunol A and B (1 and 2) are of a novel bicyclo[7.4.0] tridecane carbon skeleton and faraunatin (3) is an unprecedented prenylated bicyclogermacrene. Compounds 1-3 are cytotoxic against P388 cells.
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收藏
页码：8855 / 8858
页数：4
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