PROTON MAGNETIC-RESONANCE STUDIES OF THE STATES OF IONIZATION OF HISTIDINES IN NATIVE AND MODIFIED SUBTILISINS

被引：36
作者：
JORDAN, F [1 ]
POLGAR, L [1 ]
TOUS, G [1 ]
机构：
[1] HUNGARIAN ACAD SCI,BIOL RES CTR,INST ENZYMOL,H-1502 BUDAPEST,HUNGARY
来源：
BIOCHEMISTRY | 1985年 / 24卷 / 26期
关键词：
D O I：
10.1021/bi00347a031
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：7711 / 7717
页数：7
相关论文
共 23 条
[1]   N-15 NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY - STATE OF HISTIDINE IN CATALYTIC TRIAD OF ALPHA-LYTIC PROTEASE - IMPLICATIONS FOR CHARGE-RELAY MECHANISM OF PEPTIDE-BOND CLEAVAGE BY SERINE PROTEASES [J].
BACHOVCHIN, WW ;
ROBERTS, JD .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (26) :8041-8047
[2]   DETERMINATION OF CONCENTRATION OF HYDROLYTIC ENZYME SOLUTIONS - ALPHA-CHYMOTRYPSIN TRYPSIN PAPAIN ELASTASE SUBTILISIN AND ACETYLCHOLINESTERASE [J].
BENDER, ML ;
BEGUECAN.ML ;
BLAKELEY, RL ;
BRUBACHER, LJ ;
FEDER, J ;
GUNTER, CR ;
KEZDY, FJ ;
KILLHEFFER, JV ;
MARSHALL, TH ;
MILLER, CG ;
ROESKE, RW ;
STOOPS, JK .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1966, 88 (24) :5890-+
[3]   P-31 NMR OF DIISOPROPYL PHOSPHORYL ALPHA-CHYMOTRYPSIN AND CATECHOL CYCLIC PHOSPHATE ALPHA-CHYMOTRYPSIN - DIRECT OBSERVATION OF 2 CONFORMATIONAL ISOMERS [J].
GORENSTEIN, DG ;
FINDLAY, JB .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1976, 72 (02) :640-645
[4]   PROTON NUCLEAR MAGNETIC-RESONANCE EVIDENCE FOR THE ABSENCE OF A STABLE HYDROGEN-BOND BETWEEN THE ACTIVE-SITE ASPARTATE AND HISTIDINE-RESIDUES OF NATIVE SUBTILISINS AND FOR ITS PRESENCE IN THIOLSUBTILISINS [J].
JORDAN, F ;
POLGAR, L .
BIOCHEMISTRY, 1981, 20 (22) :6366-6370
[5]  
JORDAN F, 1982, STERIC EFFECTS BIOMO, P271
[6]   DIRECT DETERMINATION OF THE PROTONATION STATES OF ASPARTIC ACID-102 AND HISTIDINE-57 IN THE TETRAHEDRAL INTERMEDIATE OF THE SERINE PROTEASES - NEUTRON STRUCTURE OF TRYPSIN [J].
KOSSIAKOFF, AA ;
SPENCER, SA .
BIOCHEMISTRY, 1981, 20 (22) :6462-6474
[7]   SERINE PROTEASES - STRUCTURE AND MECHANISM OF CATALYSIS [J].
KRAUT, J .
ANNUAL REVIEW OF BIOCHEMISTRY, 1977, 46 :331-358
[8]   ZYMOGEN ACTIVATION IN SERINE PROTEINASES - PROTON MAGNETIC-RESONANCE PH TITRATION STUDIES OF 2 HISTIDINES OF BOVINE CHYMOTRYPSINOGEN-A AND CHYMOTRYPSIN-A-ALPHA [J].
MARKLEY, JL ;
IBANEZ, IB .
BIOCHEMISTRY, 1978, 17 (22) :4627-4640
[9]  
MARKLEY JL, 1979, BIOL APPLICATIONS MA, P397
[10]   HISTIDYL AND TYROSYL RESIDUE IONIZATION STUDIES OF SUBTILISIN NOVO [J].
OMAR, S ;
BROWN, MF ;
SILVER, P ;
SCHLEICH, T .
BIOCHIMICA ET BIOPHYSICA ACTA, 1979, 578 (02) :261-268
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