CHARACTERISTICS OF LIPID AND PHOSPHOLIPID-COMPOSITION OF THE SERUM AND RED-CELL MEMBRANES IN CHILDREN WITH HEMORRHAGIC VASCULITIS

Thin-layer chromatography examination of serum and red cell membrane lipids and phospholipids has been conducted in 37 children with hemorrhagic vasculitis. The authors found: huperlipidemia resultant from high concentrations of triglycerides, changes in phospholipid fractions due to a relative rise in the level of phosphatidylethanolamine, altered spectrum of red cell membrane lipids due to a significant increase in free cholesterol against low triglycerides. The above shifts may cause hypercoagulation and microcirculatory affections. The conclusion is made on the necessity of correcting impaired lipid spectrum of blood plasma and red cell membrane when conducting basic therapy of hemorrhagic vasculitis.