HIGHLY STEREOSELECTIVE RADICAL-ADDITION TO A TRISUBSTITUTED ALKENE BY LOW-TEMPERATURE PHOTOLYSIS OF THIOHYDROXAMIC ESTERS

被引：34
|
作者：
SCOTT, DM [1 ]
MCPHAIL, AT [1 ]
PORTER, NA [1 ]
机构：
[1] DUKE UNIV,PAUL M GROSS CHEM LAB,DEPT CHEM,DURHAM,NC 27706
来源：
TETRAHEDRON LETTERS | 1990年 / 31卷 / 12期
基金：
美国国家卫生研究院; 美国国家科学基金会;
关键词：
D O I：
10.1016/S0040-4039(00)88852-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Low temperature carbon radical addition to α,β-unsaturated amides of trans-2,5-dimethylpyrrolidine was achieved in high yield with high diastereoselectivity by photolysis of Barton esters. Use of an olefin substituted with three electron withdrawing groups provides synthetic versatility and regiospecificity. © 1990.
引用
收藏
页码：1679 / 1682
页数：4
相关论文
共 13 条
12